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Dr Aleksandra Lange

Director & Cardiologist LifePulse Cardiology
Senior Lecturer University of Qld

FRACP | FCSANZ | RANZCR Level A CTCA 
FESC | DM (Edinburgh) | MB ChB

Key Areas of Expertise

  • Advanced Cardiac Imaging

  • Heart Failure (HFpEF & HFrEF)

  • Coronary Artery Disease (CAD)

  • Cardio-Oncology

  • Preventive Cardiology

  • CT Coronary Angiography (CTCA)

  • Coronary Artery Calcium (CAC) Scoring

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Clinic Approach

Combines advanced cardiovascular imaging with a deep understanding of cardiac physiology to guide diagnosis and treatment. Her practice focuses on:

  • Early detection of cardiovascular disease

  • Personalised risk assessment and prevention strategies

  • Integration of imaging into clinical decision-making

  • Long-term management of complex cardiac conditions

Email: a.lange@lifepulsecardiology.com.au

Dr Aleksandra Lange is a consultant cardiologist and academic with expertise in cardiovascular imaging, heart failure, coronary artery disease, and cardio-oncology. She is a Senior Lecturer at the University of Queensland and is actively involved in numerous research projects focused on improving the diagnosis and management of cardiovascular disease.

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Her clinical approach integrates advanced imaging (including echocardiography, CT coronary angiography (CTCA), and coronary artery calcium (CAC) scoring) to deliver precise, personalised, and evidence-based care. She has a particular focus on heart failure with preserved ejection fraction (HFpEF), coronary artery disease (CAD), cardio-oncology, and preventive cardiology, with an emphasis on early detection, risk stratification, and long-term cardiovascular health.

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Dr Lange has made internationally recognised contributions to cardiac imaging, including pioneering work in three-dimensional echocardiography and the development of novel diagnostic approaches to better characterise cardiac function. At LP Cardiology, she is committed to providing thoughtful, patient-centred care supported by the latest advances in cardiovascular medicine.

Research & Publications

Publications

  1. Palka P, Hilling-Smith R, Swann R, Allwood S, Moore A, Bian C, Lange A. Left ventricular to left atrial volume ratio in the assessment of filling pressure in patients with dyspnoea and preserved ejection Fraction. Front Cardiovasc Med. 2024;11:1357006.

  2. Lange A, Palka V, Bian C, Huntress H, Morgan J, Allwood S, Swann R, Palka P. Left heart remodelling in hypertensive patients: a comprehensive echocardiography and computed tomography study. Front Cardiovasc Med. 2023;10:1295537.

  3. Lange A, Huntress H, Steindl J, Palka P. Incremental role of CT coronary angiography in the assessment of left ventricular diastolic function. Open Heart. 2021;8:e001566.

  4. Palka P, Lange A, Galbraith A, Duhig E, Clarke BE, Parsonage W, Donnelly JE, Stafford WJ, Burstow DJ. The role of left and right ventricular early diastolic Doppler tissue echocardiographic indices in the evaluation of acute rejection in orthotopic heart transplant. J Am Soc of Echocardiogr. 2005;18:107-115.

  5. Palka P, Lange A, Atherton J, Stafford WJ, Burstow DJ. Biventricular diastolic behaviour in patients with hypertrophic and hereditary hemochromatosis cardiomyopathies. Eur J Echocardiography. 2004;5:356-366.

  6. Palka P, Lange A, Ward C. A fatal case of idiopathic restrictive cardiomyopathy in infant. Cardiol Young. 2003;13:469-471.

  7. Palka P, Lange A, Burstow DJ. Different presentation of hypertrophic cardiomyopathy in monozygotic twins. Heart. 2003;89:751.

  8. Lange A, Coleman DM, Palka P, Burstow DJ, Wilkinson JL, Godman MJ. The effect of catheter device closure of atrial septal defect on left ventricular systolic and diastolic function. Am J Cardiol. 2003;91:104-8.

  9. Adsett M, West MJ, Galbraith A, Duhig E, Lange A, Palka P. Eosinophilic heart: Marked left ventricular wall thickening and myocardial dysfunction improving with corticosteroid therapy. Echocardiography. 2003;20;369-374.

  10. Palka P, Lange A, Tam R, Burstow, DJ. Needle in the heart. Circulation. 2003;107:e56-e57.

  11. Palka P, Lange A, Clarke B, Duhig E, Galbraith A. Echocardiographic description of recurrent idiopathic giant-cell myocarditis in cardiac allograft. Circulation. 2003;108:e1-e3.

  12. Palka P, Lange A, Donnelly JE, Nihoyannopoulos P, Burstow DJ. Doppler tissue echocardiographic features of cardiac amyloidosis. J Am Soc Echocardiogr. 2002;15:1353-60.

  13. Palka P, Harrocks S, Lange A, Burstow DJ, O’Brien MF. Primary aortic valve replacement with cryopreserved aortic allograft – an echocardiographic follow-up study of 570 patients. Circulation. 2002;105:61-66.

  14. Lange A, Palka P, Donnelly JE, Burstow DJ. Quantification of mitral regurgitation orifice area by three-dimensional echocardiography: comparison with effective regurgitant orifice area by PISA method and proximal regurgitant jet diameter. Int J Cardiol. 2002;86:87-98.

  15. Palka P, Macdonald G, Lange A, Burstow DJ. The role of Doppler left ventricular filling indices and tissue Doppler echocardiography in the assessment of cardiac involvement in hereditary hemochromatosis. J Am Soc Echocardiogr.  2002;15:884-890.

  16. Palka P, Lange A, Burstow DJ. Doppler myocardial velocity gradient as a new diagnostic index for the assessment of myocardial disease. Pol Merk Lek. 2001;61:72-78.

  17. Palka P, Anderson B, Lange A. Large coiled right ventricular outflow tract thrombus resolved after thrombolytic therapy. Heart. 2001;86:505.

  18. Lange A, Palka P, Burstow DJ, Godman MJ. Three-dimensional echocardiography historical development and current applications. J Am Soc Echocardiogr. 2001;14:403-12.

  19. Palka P, Lange A, Donnelly JE, Nihoyannopoulos P. Differentiation between restrictive cardiomyopathy and constrictive pericarditis by early diastolic Doppler myocardial velocity gradient at the posterior wall. Circulation. 2000;102:655-662.

  20. Dutka DP, Donnelly JE, Palka P, Lange A, Nunez DJ, Nihoyannopoulos P. Echocardiographic characterisation of cardiomyopathy in Friedreich’s ataxia with tissue Doppler echocardiographically derived myocardial velocity gradients. Circulation. 2000;102:1276-1282.

  21. Lange A, Mankad P, Walayat M, Palka P, Burns JE, Godman MJ. Transthoracic three-dimensional echocardiography in the preoperative assessment of atrioventricular septal defect morphology. Am J Cardiol. 2000;85:630-635.

  22. Palka P, Lange A, Ferrington C, Fox KAA. Mean myocardial velocity mapping in quantifying regional myocardial contractile reserve with impaired left ventricular systolic function: Doppler myocardial imaging study. J Am Soc Echocardiogr. 2000;13:96-107.

  23. Palka P, Lange A, Nihoyannopoulos P. The effect of long-term training on age-related left ventricular changes by Doppler myocardial velocity gradient. Am J Cardiol. 1999;84:1061-1067.

  24. Lange A, Connell M, Palka P, Walayat M, Mankad P, Burns JE, Shaw TRD, Nowicki A, McDicken WN, Godman MJ, Fox KAA. A novel method for 3-dimensional dynamic reconstruction of cardiac ultrasound images: Interactive changing of cut-planes, threshold and opacity. Heart. 1998;79:P15.

  25. Lange A, Palka P, Nowicki A, Olszewski R, Anderson T, Adamus J, Sutherland GR, Fox KAA. Three-dimensional echocardiographic evaluation of left ventricular volume: Comparison of Doppler myocardial imaging and standard grey-scale imaging with cineventriculography - an in vitro and in vivo study. Am Heart J. 1998;135:970-9.

  26. Caso P, Ascione L, Lange A, Palka P, Mininni N, Sutherland GR. Diagnostic value of transoesophageal echocardiography in the assessment of congenitally corrected transposition of great arteries in adult patients. Am Heart J. 1998;135:43-50.

  27. Moore MP, Spencer T, Salter DM, Kearney PP, Shaw TRD, Starkey IR, Fitzgerald PJ, Erbel R, Lange A, McDicken WN, Sutherland GR, Fox KAA. Characterisation of coronary atherosclerotic morphology by spectral analysis of radiofrequency signal: in vitro intravascular ultrasound study with histological and radiological validation. Heart. 1998;79:459-67.

  28. Lange A, Walayat M, Turnbull CM, Palka P, Mankad P, Sutherland GR, Godman MJ. Assessment of atrial septal defect morphology by transthoracic three-dimensional echocardiography using standard grey scale and Doppler myocardial imaging techniques: Comparison with magnetic resonance imaging and intraoperative findings. Heart. 1997;78;382-389.

  29. Palka P, Lange A, Fleming AD, Donnelly JE, Dutka DP, Starkey IR, Shaw TRD, Sutherland GR, Fox KAA. Differences in myocardial velocity gradient measured throughout the cardiac cycle in hypertrophic cardiomyopathy, athletes and patients with left ventricular hypertrophy due to hypertension. J Am Coll Cardiol. 1997;30:760-768.

  30. Palka P, Lange A, Wright RA, Starkey IR, Fleming AD, Bouki KP, Sutherland GR, Shaw TRD, Fox KAA. Myocardial velocity gradient measured throughout the cardiac cycle in dilated cardiomyopathy hearts - a potential new parameter of systolic and diastolic myocardial function by Doppler myocardial imaging. Eur J Ultrasound. 1997;5:141-154.

  31. Lange A, Palka P, Caso P, Fenn LN, Olszewski R, Ramo MP, Shaw TRD, Nowicki A, Fox KAA, Sutherland GR. Doppler myocardial imaging vs. B-mode grey-scale imaging: A comparative in vitro and in vivo study into their relative efficacy in endocardial boundary detection. Ultrasound Med Biol. 1997;23:69-75.

  32. Sutherland GR, Lange A, Palka P, Grubb N, Fleming A, McDicken WN. Does Doppler myocardial imaging give new insights or simply old information revisited? Heart. 1996;76:197-199.

  33. Palka P, Lange A, Fleming AD, Fenn LN, Bouki KP, Shaw TRD, Fox KAA, McDicken WN, Sutherland GR. Age-related transmural peak mean velocities and peak velocity gradients by Doppler myocardial imaging in normal subjects. Eur Heart J. 1996;17:940-50.

  34. Bouki KP, Lange A, Palka P, Moran CM, Fenn LN, Wright RA, Fox KAA, McDicken WN, Sutherland GR. Regional variation of ultrasonic integrated backscatter in normal and myopathic left ventricles-a new multi-view approach. Eur Heart J. 1996;17:1747-55.

  35. Sutherland GR, Palka P, Lange A, Grubb N, McDicken WN. Doppler myocardial imaging. Cardiovascular Imag. 1996;8:251-255.

  36. Lange A, Wright RA, Al-Nafusi A, Sang C, Palka P, Sutherland GR. Doppler myocardial imaging: a potential better method of data acquisition for three-dimensional echocardiography. J Am Soc Echocardiogr. 1996;9:918-921.

  37. Lange A, Sutherland GR. Imaging of intracardiac thrombi. Current Medical Literature Thrombosis. 1995;5:3-5

  38. Palka P, Lange A, Fleming A, Sutherland GR, Fenn LN, McDicken WN. Doppler tissue imaging: Myocardial wall motion velocities in normal subjects. J Am Soc Echocardiogr. 1995;8:659-68.

  39. Lange A, Moran CM, Palka P, Fenn LN, Sutherland GR, McDicken WN. The variation of integrated backscatter in human hearts using differing ultrasonic views. J Am Soc Echocardiogr 1995;8:830-8.

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Book Chapters

  1. Sutherland GR, Lange A, Palka P, McDicken NW. Doppler Myocardial Imaging. In: Perez JE & Lang RM, eds. Echocardiography and Cardiovascular Function: Tools for the Next Decade. Kluwer Academic Publishers, Dordrecht / Boston / London; 1997:241-268.

  2. Lange A, Palka P. Atrioventricular Septal Defects. Guide to Rare Disorders In: National Organization for Rare Disorders, Inc (NORD): Lippincott, Williams & Wilkins, Philadelphia, PA; 2002:43-44.​​

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